Superman has nothing to be worried about
Scott Shaw tracks comic weirdness in his column for Comic Book Resources called Oddball Comics (archives). How weird are we talking about? How 'bout:
see Jughead pass out sniffing glue!
and my personal fave, a comic to promote Maine sardines to children (talk about a tough sell) -- Ricky And Debbie In Sardineland!
More unusual and sometimes not-so-PC covers at Joe Bates site.